Perry Bible Fellowship Comic
(View full version of this strip)
This isn't what I would call a webcomic because it seems more representive of newspaper comics. This comic takes the wit of Farside, and the sadistic nature of Exploding Dog and combines it with wonderfully drawn colourful illustrations.
Even if you've ignored my infrequent posts about webcomics, you owe yourself a look at this one.
Link (via Waxy)